Dose verification to cochlea during gamma knife radiosurgery of acoustic schwannoma using MOSFET dosimeter.
| Autor: | Sharma SD; Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, CTCRS Building, Anushaktinagar, Mumbai, India. sdsbarc@gmail.com, Kumar R, Akhilesh P, Pendse AM, Deshpande S, Misra BK |
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| Jazyk: | angličtina |
| Zdroj: | Journal of cancer research and therapeutics [J Cancer Res Ther] 2012 Oct-Dec; Vol. 8 (4), pp. 528-31. |
| DOI: | 10.4103/0973-1482.106528 |
| Abstrakt: | Aim: Dose verification to cochlea using metal oxide semiconductor field effect transistor (MOSFET) dosimeter using a specially designed multi slice head and neck phantom during the treatment of acoustic schwannoma by Gamma Knife radiosurgery unit. Materials and Methods: A multi slice polystyrene head phantom was designed and fabricated for measurement of dose to cochlea during the treatment of the acoustic schwannoma. The phantom has provision to position the MOSFET dosimeters at the desired location precisely. MOSFET dosimeters of 0.2 mm x 0.2 mm x 0.5 μm were used to measure the dose to the cochlea. CT scans of the phantom with MOSFETs in situ were taken along with Leksell frame. The treatment plans of five patients treated earlier for acoustic schwannoma were transferred to the phantom. Dose and coordinates of maximum dose point inside the cochlea were derived. The phantom along with the MOSFET dosimeters was irradiated to deliver the planned treatment and dose received by cochlea were measured. Results: The treatment planning system (TPS) estimated and measured dose to the cochlea were in the range of 7.4 - 8.4 Gy and 7.1 - 8 Gy, respectively. The maximum variation between TPS calculated and measured dose to cochlea was 5%. Conclusion: The measured dose values were found in good agreement with the dose values calculated using the TPS. The MOSFET dosimeter can be a suitable choice for routine dose verification in the Gamma Knife radiosurgery. |
| Databáze: | MEDLINE |
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