Thrombolysis for stroke caused by infective endocarditis: an illustrative case and review of the literature.

Autor: Ong E; Stroke Unit, Neurology Department, Neurological Hospital, Lyon, 59, boulevard Pinel, 69677 Bron Cedex, France., Mechtouff L, Bernard E, Cho TH, Diallo LL, Nighoghossian N, Derex L
Jazyk: angličtina
Zdroj: Journal of neurology [J Neurol] 2013 May; Vol. 260 (5), pp. 1339-42. Date of Electronic Publication: 2013 Jan 05.
DOI: 10.1007/s00415-012-6802-1
Abstrakt: Infective endocarditis represents a classical contra-indication to thrombolysis for acute ischemic stroke due to a potential increased risk of intracranial hemorrhage. However, some case reports have suggested safety and potential efficacy of intravenous or intra-arterial thrombolysis in stroke related to infective endocarditis. We present a case of ischemic stroke related to infective endocarditis who was treated with intravenous tissue plasminogen activator within the first 3 h of symptoms onset and subsequently developed symptomatic multifocal intracerebral hemorrhages, and summarize currently available data on this issue.
Databáze: MEDLINE