| Autor: |
Downward AM; Department of Chemistry, University of Canterbury, Private Bag 4800, Christchurch, New Zealand., Jane RT, Polson MI, Moore EG, Hartshorn RM |
| Jazyk: |
angličtina |
| Zdroj: |
Dalton transactions (Cambridge, England : 2003) [Dalton Trans] 2012 Dec 21; Vol. 41 (47), pp. 14425-32. |
| DOI: |
10.1039/c2dt31986a |
| Abstrakt: |
Heterodinuclear ruthenium(II)-cobalt(III) complexes have been prepared as part of investigations into a new approach to selective cancer treatment. A cobalt(III) centre bearing amine ligands, which serve as models for cytotoxic nitrogen mustard ligands, is connected by a bridging ligand to a ruthenium(II)-polypyridyl moiety. Upon excitation of the ruthenium centre by visible light, electron transfer to the cobalt(III) centre results in reduction to cobalt(II) and consequent release of its ligands. We have synthesised several such structures and demonstrated their ability to release ligands upon excitation of the ruthenium centre by visible light. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
