[Endogenous sex hormone testosterone and haemostatic factors in young men after myocardial infarction].

Autor:	Kerimova KN, Bakhshaliev AB, Gadzhiev RF, Gamidova ÉS
Jazyk:	ruština
Zdroj:	Kardiologiia [Kardiologiia] 2012; Vol. 52 (6), pp. 24-7.
Abstrakt:	Objectives: To compare levels of haemostatic factors and sex hormones in young men after myocardial infarction, to study relationship between sex hormones and factors of hemostasis. Methods: We studied 32 men aged 30-50 years with diagnosis of myocardial infarction. Patients were divided into 2 groups according to age: group 1 - 11 patients aged 30-39 years, group 2 - 21 patients aged of 40-50 years. Levels of sex hormones were measured by IFA. Level of fibrinogen, prothrombin index, plasma recalcification time, fibrinolytic activity, indices of aggregation and disaggregation were also determined. Results: Testosterone level in the group I was more decreased in comparison with the Group 2 and level of fibrinogen was higher in the group 1 (3.9+/-0,7) in comparison with the group II (3.1+/-0.8; p<0.05). Pearsons correlation between estradiol and fibrinogen in the group 1 was 0.613 (p<0.05). No such relationship was found in the group 2. Pearsons correlation between testosterone and prothrombin index was 0,477 (p<0.009). Conclusion: Endogenous testosterone level is one of the factors which influence haemostatic system, but this effect is not well-defined and requires further study.
Databáze:	MEDLINE
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