Executive attention and working memory in narcoleptic outpatients.

Autor: Moraes M; Sleep Medicine Advanced Research Group, Division of Clinical Neurology, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, SP, Brazil., Rossini S, Reimão R
Jazyk: angličtina
Zdroj: Arquivos de neuro-psiquiatria [Arq Neuropsiquiatr] 2012 May; Vol. 70 (5), pp. 335-40. Date of Electronic Publication: 2012 Feb 09.
DOI: 10.1590/s0004-282x2012005000007
Abstrakt: Objective: This pioneering study aimed to evaluate executive attention and working memory in Brazilian narcoleptic outpatients.
Methods: Narcoleptic group: 19 treated narcoleptic outpatients (13 F; 6 M) (mean age=37.58; SD = 8.93); control group: 19 subjects (15 F; 4 M) (mean age=34.42; SD=12.31).
Instruments: Epworth Sleepiness Scale - Brazilian Portuguese Version (ESS-BR), Victoria Stroop Test (VST), Trail Making Test (TMT) and Letter-Number Sequencing (LNS) of WAIS-III.
Results: Significant difference at Excessive Daytime Sleepiness (EDS) (p<0.001) and at working memory (p=0.009) with worse results for narcoleptic patients. Patients were slower at VST-1 (p=0.002), VST-2 (p=0.045) and at TMT-A (p=0.016), TMT-B (p=0.006) and B-A (p=0.024).
Conclusion: Narcoleptic patients showed higher degrees of EDS, an impaired executive attention at a temporal level and lower performance in working memory when compared to normal controls.
Databáze: MEDLINE