| Autor: |
Kyne SH; WestChem Department of Pure and Applied Chemistry, Thomas Graham Building, 295 Cathedral Street, Glasgow, UK G1 1XL., Percy JM, Pullin RD, Redmond JM, Wilson PG |
| Jazyk: |
angličtina |
| Zdroj: |
Organic & biomolecular chemistry [Org Biomol Chem] 2011 Dec 21; Vol. 9 (24), pp. 8328-39. Date of Electronic Publication: 2011 Nov 07. |
| DOI: |
10.1039/c1ob06372c |
| Abstrakt: |
Difluoroalkenylzinc reagents prepared from 1-(2'-methoxy-ethoxymethoxy)-2,2,2-trifluoroethane and 1-(N,N-diethylcarbamoyloxy)-2,2,2-trifluoroethane at ice bath temperatures underwent Negishi coupling with a range of aryl halides in a convenient one pot procedure. While significant differences between the enol acetal and carbamate reagents were revealed, the Negishi protocol compared very favourably with alternative coupling procedures in terms of overall yields from trifluoroethanol. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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