Radio-guided occult lesion localisation for breast lesions under computer-aided MRI guidance: the first experience and initial results.

Autor: Yilmaz MH; Department of Radiology, Istanbul University, Cerrahpasa Medical School, Istanbul, Turkey., Kilic F, Icten GE, Aydogan F, Ozben V, Halac M, Olgun DC, Gazioglu E, Celik V, Uras C, Altug ZA
Jazyk: angličtina
Zdroj: The British journal of radiology [Br J Radiol] 2012 Apr; Vol. 85 (1012), pp. 395-402. Date of Electronic Publication: 2011 Oct 18.
DOI: 10.1259/bjr/30798119
Abstrakt: Objective: The purpose of this study was to present an alternative technique for the pre-operative localisation of solely MRI-detected suspicious breast lesions using a computer-assisted MRI-guided radio-guided occult lesion localisation (ROLL) technique.
Methods: Between January 2009 and June 2010, 25 females with a total of 25 suspicious breast lesions that could be detected only by MRI, and for whom breast surgery was planned, underwent the computer-assisted MRI-guided ROLL technique. A seven-channel biopsy breast array coil and computerised diagnostic workstation were used for the localisation procedure. Three-phase dynamic contrast-enhanced axial images were taken. After investigating the localisation co-ordinates with the help of intervention software on a workstation, an 18 G coaxial cannula was placed in the exact position determined. Following verification of the cannula position by additional axial scans, (99m)Tc-labelled macroalbumin aggregate and MRI contrast material were injected. Post-procedure MRI scans were used to confirm the correct localisation.
Results: All the procedures were technically successful. The mean lesion size was 10.8 mm (range: 4-25 mm). The mean total magnet and the mean localisation times were 28.6 min (range: 18-46 min) and 13.1 min (range: 8-20 min), respectively. Grid and pillar methods were used for localisation in 24 procedures and 1 procedure, respectively. On histopathological examination, 6 malignant, 10 high-risk and 9 benign lesions were identified. All patients tolerated the procedure well. There were no major complications.
Conclusion: This is the first report documenting the application of MRI-guided ROLL. Based on our preliminary results, this technique is very efficient and seems to be a good alternative to wire localisation.
Databáze: MEDLINE