Group B Streptococcus in a cohort of HIV-infected pregnant women: prevalence of colonization, identification and antimicrobial susceptibility profile.

Autor: Joao EC; Department of Infectious Diseases, Hospital dos Servidores do Estado, Rua Sacadura Cabral 178, Pesquisa Clínica Saúde, Rio de Janeiro, RJ, Brazil. esau@uninet.com.br, Gouvêa MI, Menezes JA, Matos HJ, Cruz ML, Rodrigues CA, de Souza MJ, Fracalanzza SE, Botelho AC, Calvet GA, Grinsztejn BG
Jazyk: angličtina
Zdroj: Scandinavian journal of infectious diseases [Scand J Infect Dis] 2011 Sep; Vol. 43 (9), pp. 742-6. Date of Electronic Publication: 2011 Jun 15.
DOI: 10.3109/00365548.2011.585178
Abstrakt: Group B Streptococcus (GBS) is a leading cause of infectious morbidity in newborns. We describe the prevalence of GBS colonization and the serotypes and antibiotic susceptibility profiles of isolates obtained from a cohort of human immunodeficiency virus (HIV)-infected pregnant women. This was a cross-sectional study at a centre for the prevention of mother-to-child transmission of HIV. Vaginal and rectal swabs were collected at 35-37 weeks of gestation from 158 eligible women. GBS isolates were serotyped and antimicrobial susceptibility tests performed. Patient sociodemographic characteristics, CD4 counts and viral loads were abstracted from records. The overall anogenital prevalence of GBS colonization was 49/158 (31.0%): 40/158 (25.3%) for vagina, 19/158 (12.0%) for rectum and 10/158 (6.3%) for both. Predominant serotypes were Ib (34.9%) and Ia (25.6%). All were penicillin-susceptible. Two were resistant to erythromycin (4.0%) and one to clindamycin (2.0%). The colonization rate by GBS was high in this cohort. Serotype Ib was the most frequently identified.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje