| Autor: |
Okorokov PL, Anikhovskaia IA, Volkov IE, Iakovlev MIu |
| Jazyk: |
ruština |
| Zdroj: |
Fiziologiia cheloveka [Fiziol Cheloveka] 2011 Mar-Apr; Vol. 37 (2), pp. 138-41. |
| Abstrakt: |
We studied serum level of intestinal flora endotoxin (LPS) in 45 children and adolescents aged 3-17 years old with diabetes mellitus type 1. Levels of endotoxin, were significantly elevated in type 1 diabetic patients (2.89 +/- 0.33 Eu/ml) compared with control (0.4 +/- 0.03 Eu/ml). There was significant difference in serum LPS levels in patients with type 1 diabetes onset (3.93 +/- 0.79 Eu/ml) compared with children and adolescent with old time diabetes (2.37 +/- 0.27 Eu/ml). These results have a major implication on our understanding of the role of gut flora endotoxin in pathogenesis of type 1 diabetes. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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