Lip squamous cell carcinoma in a Brazilian population: epidemiological study and clinicopathological associations.
| Autor: | Souza RL; Health Science Programme, State University of Montes Claros, Montes Claros, Brazil., Fonseca-Fonseca T, Oliveira-Santos CC, Corrêa GT, Santos FB, Cardoso CM, Sant' Ana-Haikal D, Guimarães AL, Batista-De Paula AM |
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| Jazyk: | angličtina |
| Zdroj: | Medicina oral, patologia oral y cirugia bucal [Med Oral Patol Oral Cir Bucal] 2011 Sep 01; Vol. 16 (6), pp. e757-62. Date of Electronic Publication: 2011 Sep 01. |
| DOI: | 10.4317/medoral.16954 |
| Abstrakt: | Objectives: It was evaluated epidemiological aspects of primary lip squamous cell carcinoma (LSCC) and its associations with clinicopathological factors. Study Design: This retrospective, cross-sectional study analysed a socio-demographic, clinical, and morphological data of HNSCC in a Brazilian population (n=30). Data analysis included descriptive statistics and bivariate analyses using the chi-square and Fisher 's exact tests to compare the variables. Results: The LSCC represented 10.8% of all oral cavity squamous cell carcinoma. Lip malignant disease was more prevalent in elderly men, with male-to-female ratio of 5:1. Lower lip was more affected. It was observed high rates of chronic solar exposure, and tobacco and alcohol drinking habits. Clinically, early TNM staging, small tumour lesions, and non-metastatic disease were predominant findings. It was identified a high frequency of well differentiated tumor samples. Worse Karnofsky performance status was associated with cervical metastasis. Conclusions: Our findings showed that LSCC patients exhibited similar epidemiological and clinical profiles as noted in other studies. Still, the occurrence of metastatic disease was associated with a worse physical performance status of the LSCC patients during diagnosis. |
| Databáze: | MEDLINE |
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