Hemorrhagic leukoencephalitis linked to Epstein-Barr virus in an adult patient.

Autor: Befort P; Service de Réanimation Médicale Assistance Respiratoire, Hôpital Gui de Chauliac, 80 avenue Augustin Fliche, 34295 Montpellier Cedex 5, France. p-befort@chu-montpellier.fr, Gaillard N, Roubille C, Quellec AL
Jazyk: angličtina
Zdroj: Clinical neurology and neurosurgery [Clin Neurol Neurosurg] 2010 Nov; Vol. 112 (9), pp. 829-31. Date of Electronic Publication: 2010 Jul 25.
DOI: 10.1016/j.clineuro.2010.06.017
Abstrakt: We report a case of an adult patient who presented a febrile coma linked to Epstein-Barr virus (EBV) encephalitis. EBV polymerase chain reaction (PCR) was positive in cerebrospinal fluid (CSF) and blood serology and PCR in blood was consistent with an EBV reactivation. First cerebral magnetic resonance imaging (MRI) at day 1 was normal but a second MRI at day 13 showed anomaly compatible with a hemorrhagic leukoencephalitis. Treatment consists of intravenous corticotherapy and aciclovir during 21 days. Evolution was favourable with complete neurologic recuperation and no intercurrent lymphoma or vasculitis in 6 months follow-up.
(Copyright © 2010 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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