| Autor: |
Hsia CC; Division of Biology, University of California, San Diego, La Jolla, CA 92093, USA., Paré AC, Hannon M, Ronshaugen M, McGinnis W |
| Jazyk: |
angličtina |
| Zdroj: |
Evolution & development [Evol Dev] 2010 Mar-Apr; Vol. 12 (2), pp. 131-43. |
| DOI: |
10.1111/j.1525-142X.2010.00399.x |
| Abstrakt: |
We tested whether Artemia abd-A could repress limbs in Drosophila embryos, and found that although abd-A transcripts were produced, ABD-A protein was not. Similarly, developing Artemia epidermal cells showed expression of abd-A transcripts without accumulation of ABD-A protein. This finding in Artemia reveals a new variation in Hox gene function that is associated with morphological evolution. In this case, a HOX protein expression pattern is completely absent during early development, although the HOX protein is expressed at later stages in the central nervous system in a "homeotic-like" pattern. The combination of an absence of ABD-A protein expression in the Artemia limb primordia and the weak repressive function of Artemia UBX protein on the limb-promoting gene Dll are likely to be two reasons why homonomous limbs develop throughout the entire Artemia trunk. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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