Peripartum metabolic control in gestational diabetes.

Autor: Flores-Le Roux JA; Department of Endocrinology, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain. 94066@imas.imim.es, Chillaron JJ, Goday A, Puig De Dou J, Paya A, Lopez-Vilchez MA, Cano JF
Jazyk: angličtina
Zdroj: American journal of obstetrics and gynecology [Am J Obstet Gynecol] 2010 Jun; Vol. 202 (6), pp. 568.e1-6. Date of Electronic Publication: 2010 Mar 15.
DOI: 10.1016/j.ajog.2010.01.064
Abstrakt: Objective: We sought to evaluate intrapartum metabolic control in gestational diabetes mellitus (GDM) patients and maternal factors influencing intrapartum glycemic control and neonatal hypoglycemia risk.
Study Design: A prospective observational study included 129 women with GDM admitted for delivery. Data collected included maternal intrapartum capillary blood glucose (CBG) and ketonemia, use of insulin, and neonatal hypoglycemia.
Results: In all, 86% of maternal intrapartum CBG values fell within target range (3.3-7.2 mmol/L) without need for insulin use. There were no cases of maternal hypoglycemia or severe ketosis. Intrapartum CBG >7.2 mmol/L was associated with third-trimester glycated hemoglobin (P = .02) and lack of endocrinologic follow-up (P = .04). Risk of neonatal hypoglycemia was related with pregnancy insulin use compared with dietary control (60.5% vs 29.5%; P = .02).
Conclusion: Peripartum metabolic control in GDM patients was achieved without insulin in most cases. Intrapartum glycemic control was related with third-trimester glycated hemoglobin and with no endocrinologic follow-up. Neonatal hypoglycemia was associated with insulin use during pregnancy.
(Copyright 2010 Mosby, Inc. All rights reserved.)
Databáze: MEDLINE
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