| Autor: |
Ounnas F; Unité de Recherche Animal et Fonctionnalités des Produits Animaux (UR AFPA), Nancy University, INRA, 2 av de la forêt de Haye, Vandoeuvre-lès-Nancy Cedex, France. Faycal.Ounnas@ensaia.inpl-nancy.fr, Feidt C, Toussaint H, Marchand P, Bizec BL, Rychen G, Jurjanz S |
| Jazyk: |
angličtina |
| Zdroj: |
Environmental science & technology [Environ Sci Technol] 2010 Apr 01; Vol. 44 (7), pp. 2682-8. |
| DOI: |
10.1021/es9036786 |
| Abstrakt: |
This study investigated milk excretion kinetics of PCBs, tetra-BDE (BDE 47), and penta-BDE (BDE 99) in goats exposed to contaminated soil under controlled conditions. The animals were fed (80 days) with feed containing 5% of contaminated soil. During this exposure period, milk was analyzed weekly. At the end of the experiment the PCBs and PBDEs retained in hepatic and adipose tissues were also determined. The soil-milk carry over rates (CORs) of PCBs ranged from 6 to 62%. This result suggests that a large part of ingested soil-bound PCBs was recovered in milk. Significantly different levels between the congeners were reported in the tissues (fat, liver). BDE 47 and 99 excretions in milk achieved a plateau after 2 weeks of exposure, and their corresponding CORs were about 30%. These two congeners showed a significantly (P < 0.05) lower accumulation in the adipose tissue than the major PCB congeners. The concentrations of BDE 47 and 99 in the liver were the same as PCB concentrations. This result suggests that the low brominated congeners are submitted to the metabolism more extensively than the major PCBs. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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