| Autor: |
Znamens'ka TK, Pokhyl'ko VI, Koval'ova OM, Zadorozhna TD, Archakova TM, Rozova KV |
| Jazyk: |
ukrajinština |
| Zdroj: |
Likars'ka sprava [Lik Sprava] 2009 Apr-Jun (3-4), pp. 75-84. |
| Abstrakt: |
The work includes a research of morphological and immune-histochemical specifics of baby rats' cerebral structures in the conditions of experimental hypoxia model and with the administration of Cerebrocurin. It was ascertained that the most pronounced changes in the form of pericellular and perivascular edema, spongiform loci and loci of necrosis, with the phenomena of apoptosis and aponeuroses, occurred during severe hypoxia. Administration of Cerebrocurin in baby rats, which experienced moderate hypoxia, causes a decrease in pathological changes in cerebral structures and the approximation of the level of CD95 APO-1/Fas and Bcl-21 gene expression to their level in intact animals. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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