Autor: |
Ojeda-González MB; Service of Oncology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Spain., Alvárez-López I, Alonso-Muñoz MC, Badía-Serra J, Delgado-Latre E, de Andrés-Basauri L, López-López JJ |
Jazyk: |
angličtina |
Zdroj: |
Oncology [Oncology] 1991; Vol. 48 (1), pp. 7-12. |
DOI: |
10.1159/000226885 |
Abstrakt: |
Seventy-two patients with advanced ovarian cancer received CAP chemotherapy followed by laparotomy and 'second-effort' surgery. The overall response to CAP therapy was 80%. A complete pathological response (CPR) was obtained in 16 patients and partial microscopic (PMiR) and macroscopic responses in 7 and 33 cases, respectively. The actuarial survival for the entire group was 36% at 50 months with a median survival of 34 months. No significant differences in survival between the CPR and PMiR groups were found. Radical second-effort surgery showed a somewhat beneficial effect. The tumor size before chemotherapy (less than 5 cm) and FIGO stage III had a significantly favorable effect on response rate and survival. |
Databáze: |
MEDLINE |
Externí odkaz: |
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