| Autor: |
Coelho Lima BM; Nucleo de Doencas Infecciosas, Universidade Federal do Espirito Santo, Brazil., Golub JE, Tonani Mattos A, Freitas LB, Cruz Spano L, Espinosa Miranda A |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) [J Int Assoc Physicians AIDS Care (Chic)] 2009 Sep-Oct; Vol. 8 (5), pp. 286-90. Date of Electronic Publication: 2009 Aug 31. |
| DOI: |
10.1177/1545109709341855 |
| Abstrakt: |
We conducted a cross-sectional study in Vitória, Brazil, to assess the prevalence of human papillomavirus (HPV) infection in HIV-positive and HIV-negative women attending a sexually transmitted infection (STI)/AIDS clinic. We also investigated the presence of HPV genotypes and assessed covariates for HIV infection. Enrolled patients received a gynecological evaluation, and cervical scrape samples were collected for cytological analysis and HPV-DNA polymerase chain reaction (PCR). A blood sample was obtained to determine HIV status. HPV infection and squamous intraepithelial lesions were studied in 284 women, 112 (39.4%) HIV-positive women and 172 (60.5%) HIV-negative women. HPV-DNA was detected in 133 (46.8%). HIV-infected women were almost twice as likely to be concurrently infected with HPV than HIV-negative women (OR = 1.87 95% CI: 1.16-3.03). The high proportion of HPV detected among women attending an STI/AIDS clinic, particularly among HIV-infected women, proves the importance of screening this high-risk group in the hope of earlier detection and treatment of cervical intraepithelial neoplasia (CIN). |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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