[Chronic hepatitis B, hemosiderosis, and hepatic fibrosis in a renal graft recipient].

Autor: Zubkin ML, Pavlov ChS, Chervinko VI, Semenenko TA, Balakirev EM, Zolotarevskiĭ VB, Frolov AV, Baranova FS, Repetiĭ NG, Bakulin IG, Stanke AA, Novozhenov VG
Jazyk: ruština
Zdroj: Klinicheskaia meditsina [Klin Med (Mosk)] 2009; Vol. 87 (6), pp. 64-7.
Abstrakt: Chronic hepatitis B is a frequent concomitant disease in recipients of a renal graft that worsens results of kidney transplantation due to renal and extrarenal complications. Much rarer hemochromatosis either has genetic roots (hereditary hemochromatosis) or results from multiple blood transfusions and hemolysis during treatment by hemodialysis (secondary hemochromatosis). Combination of chronic hepatitis B and hemochromatosis increases the risk of chronic liver disease leading to cirrhosis and hepatocellular carcinoma. Success of antiviral therapy combined with massive phlebotomy is illustrated by a case of kidney transplantation to a patient with chronic hepatitis B of large duration and iron overload syndrome.
Databáze: MEDLINE