| Autor: |
Dhingra PN; Department of Veterinary Bacteriology and Virology, College of Veterinary Science, Punjab Agricultural University, Ludhiana, India., Mahajan VM |
| Jazyk: |
angličtina |
| Zdroj: |
Comparative immunology, microbiology and infectious diseases [Comp Immunol Microbiol Infect Dis] 1991; Vol. 14 (3), pp. 235-41. |
| DOI: |
10.1016/0147-9571(91)90004-w |
| Abstrakt: |
Two locally isolated strains of Chlamydia psittaci from faeces of apparently healthy sheep and conjunctiva of Holstein heifers suffering from conjunctivitis and pneumonia were used for ocular experimental studies in 7 Rhesus monkeys. Titrated (ELD50 10(3.6)/0.2 ml and 10(4.5)/0.2 ml) partially purified yolk sac suspension of each strain was instilled onto conjunctiva of each animal. The clinical and laboratory studies were followed till 8 weeks post-infection. Both the strains produced trachoma like follicles (0.3-0.5 mm dia) preferably on lower conjunctiva between 2-4 weeks of post-infection. Pannus was not observed in any of the experimental eye. Laboratory studies revealed a good correlation between reisolation, fluorescent antibody test and cytology between 2-4 weeks of post-infection. Highest complement fixing antibody titre 1:32 was recorded in 4 out of 7 animals. The studies indicated that both the animal strains had no barrier across ocular tissues in monkeys, vis-à-vis human conjunctiva. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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