Impact of obesity on surgical outcomes following open radical prostatectomy.

Autor: van Roermund JG; Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. jvanroermund@gmail.com, van Basten JP, Kiemeney LA, Karthaus HF, Witjes JA
Jazyk: angličtina
Zdroj: Urologia internationalis [Urol Int] 2009; Vol. 82 (3), pp. 256-61. Date of Electronic Publication: 2009 May 11.
DOI: 10.1159/000209353
Abstrakt: Objective: The increasing incidence of both obesity and prostate cancer (PCa) detection will confront the urologist more often with obese men having PCa. It is unknown whether obesity affects the surgical and oncological outcomes following open radical retropubic prostatectomy (RRP). Knowledge concerning this issue is relevant when counselling obese patients with PCa for RRP.
Patients and Methods: A single institution cohort study was performed including 252 men who underwent a RRP between 1992 and 2003. The surgical complications (perioperative complications, post-RRP urinary incontinence, urethral strictures) were compared between obese (BMI >30) and nonobese (BMI Results: Compared to nonobese (n = 221), obese men (n = 31) developed more frequently wound infections (16.1 vs. 4.5%; p < 0.05), urinary incontinence (25.8 vs. 8.7%; p < 0.05) as well as vesico-urethral strictures (46.2 vs. 12.3%; p < 0.05). The pathology results and the 5-year cumulative risk of PSA recurrence were comparable among both groups.
Conclusions: Compared to nonobese, obese men suffer more frequently from post-RRP urinary incontinence and vesicourethral strictures following open RRP.
(Copyright 2009 S. Karger AG, Basel.)
Databáze: MEDLINE
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