| Autor: |
Malyarenko EV; Luna Innovations Incorporated, Hampton, Virginia 23666, USA. evmaly@yahoo.com, Heyman JS, Chen-Mayer HH, Tosh RE |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of the Acoustical Society of America [J Acoust Soc Am] 2008 Dec; Vol. 124 (6), pp. 3481-90. |
| DOI: |
10.1121/1.2997431 |
| Abstrakt: |
This paper describes recent developments in the area of high-precision ultrasonic thermometry with the potential to provide on-site direct determination of radiation doses administered for cancer treatment. Conventional calorimeters used for this purpose measure radiation-induced heating in a water phantom at one point in space by means of immersed thermistors and are subject to various thermal disturbances due to Ohmic heating and interactions of the radiation with the sensor probes. By contrast, the method described here is based on a high-resolution ultrasonic system that determines the change of the speed of sound due to small temperature changes in an acoustic propagation path in the radiation-heated water, thereby avoiding such undesired thermal effects. The thermometer is able to measure tens of microkelvin changes in the water temperature averaged over the acoustic path of about 60 cm at room temperature, with root-mean-squared noise of about 5 microK. Both incandescent and ionizing radiation heating data are presented for analog and digital implementations of a laboratory prototype. This application of the ultrasonic technique opens up possibilities for a new approach to performing therapy-level radiation dosimetry for medical clinics and standards laboratories. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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