Night/day ratio as predictor of preeclampsia in normoalbuminuric, diabetic women: early signs of blood pressure disorders.

Autor: Lauszus FF; Department of Obstetrics/Gynecology, Herning Hospital, Aarhus University Hospital, Denmark. affl@ringamt.dk, Rosgaard A, Lousen T, Rasmussen OW, Klebe TM, Klebe JG
Jazyk: angličtina
Zdroj: Archives of gynecology and obstetrics [Arch Gynecol Obstet] 2009 Jun; Vol. 279 (6), pp. 829-34. Date of Electronic Publication: 2008 Nov 19.
DOI: 10.1007/s00404-008-0840-z
Abstrakt: Purpose: Day/night ratio from diurnal ambulatory blood pressure (AMBP) in pregnant women with type 1 diabetes mellitus (T1DM) and in non-diabetic women was evaluated for its association with preeclampsia, retinopathy, HbA1c, and birth weight.
Methods: One hundred and sixty-one women were recruited for AMBP performed with a Spacelab 90207 monitor. The pregnant women were 50 non-diabetic women and 111 T1DM women with normoalbuminuria and no hypertension. ANOVA, regression, and ROC curves analysis were applied.
Results: Women with simplex retinopathy had higher night/day ratio and lower birth weight than those without retinopathy. Women who developed preeclampsia had night/day ratio similar to those with simplex retinopathy. In first trimester they had higher blood pressure than those who did not develop preeclampsia.
Conclusions: Simplex retinopathy and preeclampsia are associated with a reduced night/day ratio even with normal blood pressure but night/day ratio provides no better prediction of preeclampsia than the absolute values.
Databáze: MEDLINE
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