[Orange-red light reduces the inhibition by UV-A of the proliferation of rat fibroblasts and influences their attachment in a dose-dependent fashion].

UV and UV --> ORL, the synergistic effect of the inhibitory action in both spectral regions was observed. Conversely, upon simultaneous irradiation with ORL (dose 3.6 J/cm2) and UV-A (dose 1.8 J/cm2), the inhibitory effect of ORL and UV-A weakened. Possible mechanisms of the effects are analyzed. -->
Entry Date(s): Date Created: 20080612 Date Completed: 20080630 Latest Revision: 20141120
Update Code: 20240829
PMID: 18543771
Autor: Khramov RN, Katkov IuA, Kreslavskiĭ VD, Murashev AN, Tsyganova VG, Simonova NB, Manokhin AA
Jazyk: ruština
Zdroj: Biofizika [Biofizika] 2008 Mar-Apr; Vol. 53 (2), pp. 294-8.
Abstrakt: The effects of ultraviolet-A (UV-A, lambdam = 365 nm) and orange-red light (lambdam = 625 nm) on the attachment and proliferation of embryonic skin-muscle rat fibroblasts were investigated. It was found that orange-red light (ORL) produces both the stimulatory and inhibitory actions on the attachment and proliferation of fibroblasts, whereas UV-A radiation caused only the inhibition of the processes. Upon consecutive irradiation in both variants: ORL --> UV and UV --> ORL, the synergistic effect of the inhibitory action in both spectral regions was observed. Conversely, upon simultaneous irradiation with ORL (dose 3.6 J/cm2) and UV-A (dose 1.8 J/cm2), the inhibitory effect of ORL and UV-A weakened. Possible mechanisms of the effects are analyzed.
Databáze: MEDLINE