Study of the mechanism of hemostatic effect of desmopressin.

Autor: Zubairov DM; Department of Biochemistry, Kazan State Medical University. dilja2001@mail.ru, Andrushko IA, Zubairova LD, Svintenok GY
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2007 Aug; Vol. 144 (2), pp. 200-2.
DOI: 10.1007/s10517-007-0288-3
Abstrakt: Intravenous injection of 1 microg/kg desmopressin to rabbits not only accelerated clotting of arterial blood (maximally by 59.16 +/- 8.53% after 1 h), but also increased the number of microvesicles containing the integral enzyme 5'-nucleotidase in the arterial blood from the initial level of 36.26 +/- 8.08 ncat/liter to a maximum of 99.65 +/- 15.8 ncat/liter after 15 min.
Databáze: MEDLINE