| Autor: |
Mamedalieva NM, Kalafati TI, Sidel'nikova VM, Sukhikh GT |
| Jazyk: |
ruština |
| Zdroj: |
Akusherstvo i ginekologiia [Akush Ginekol (Mosk)] 1991 Nov (11), pp. 21-4. |
| Abstrakt: |
Blood serum TBH levels were measured by enzyme immunoassay over the course of pregnancy in 40 women with normal pregnancy (controls) and 80 with a history of habitual abortions. Weekly measurements of TBH concentrations have revealed a significant reduction of its secretion over the entire pregnancy course in women with a history of habitual abortions vs. the controls (p less than 0.05; 0.01). A reduced TBH level starting from the first pregnancy trimester (4-7-fold reduction) and no manifest elevation of its concentration were the signs predicting the formation of primary placental insufficiency; the risk of its development was particularly high if these signs were associated with low placentation, detachment of the chorion, and recurring threatened abortions. A 10-fold and lower decrease of TBH level, its gradual or drastic reduction are the unfavorable signs preceding a spontaneous abortion. Therefore TBH measurements may be regarded as a screening test for the prediction and early diagnosis of developing placental insufficiency in pregnant women with a history of habitual abortions. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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