| Autor: |
Ong CN; Department of Community Occupational and Family Medicine, National University of Singapore., Chia SE, Phoon WH, Tan KT, Kok PW |
| Jazyk: |
angličtina |
| Zdroj: |
Scandinavian journal of work, environment & health [Scand J Work Environ Health] 1991 Dec; Vol. 17 (6), pp. 430-5. |
| DOI: |
10.5271/sjweh.1684 |
| Abstrakt: |
Occupational exposure to cyclohexanone was studied for 59 workers through the analysis of environmental air, alveolar air, and urinary cyclohexanol. Environmental cyclohexanone exposure was measured by personal sampling with a carbon-felt passive dosimeter. Cyclohexanone in alveolar air and cyclohexanol in urine were determined with gas chromatography with a flame ionization detector. The end-of-shift urinary cyclohexanol levels correlated well with the time-weighted average environmental cyclohexanone values (r = 0.66). Urinary cyclohexanol corrected for creatinine correlated best with cyclohexanone in air (r = 0.77); when corrected for specific gravity, it gave a similar correlation coefficient (r = 0.73). When the time-weighted average of the exposure was 25 ppm, the corresponding calculated concentration for urinary cyclohexanol was 54.5 mg/1, 23.3 mg/g of creatinine, or 43.5 mg/l at a specific gravity of 1.018. The relationship between cyclohexanone exposure and its concentration in exhaled breath was found to be poorer than that for cyclohexanone exposure and the urinary metabolite (r = 0.51). |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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