[The impact of large vessel proximity on effectiveness of radiofrequency ablation of hepatocellular carcinoma: a controlled study].

Autor: Seror O; Service de Radiologie, Hôpital Jean Verdier, Assistance Publique-Hôpitaux de Paris, avenue du 14 Juillet, 93140 Bondy. olivier.seror@jvr.aphp.fr, N'Kontchou G, Muhammad M, Barrucand C, Tin Tin Htar M, Assaban M, Haddar D, Trinchet JC, Beaugrand M, Sellier N
Jazyk: francouzština
Zdroj: Journal de radiologie [J Radiol] 2007 Sep; Vol. 88 (9 Pt 1), pp. 1157-64.
DOI: 10.1016/s0221-0363(07)89927-6
Abstrakt: Purpose: To evaluate the risk of radiofrequency ablation treatment failure for hepatocellular carcinomas (HCC) next to large vessels.
Materials and Methods: Between May 2000 and October 2002, from a total of 83 patients treated by radiofrequency ablation for HCC in a single center, 13 patients with tumoror=3 mm in diameter (Group A) were matched with 13 patients with similar size tumors located away from large vessels (Group B). Immediate response and recurrence rate were evaluated on CT.
Results: After mean follow-up interval of 39+/-16.5 months for Group A and 39+/-14 months for Group B, local recurrence rates were 7/12 versus 1/12 respectively (p=0.03). For Group A, 6/7 local recurrences clearly contacted a large vessel.
Conclusion: The cooling effect from flowing blood in large vessels markedly increases the rate of local failure of radiofrequency ablation for small HCC located near large vessels.
Databáze: MEDLINE
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