[Oxidative phosphorylation in liver mitochondria in toxic form of experimental form of influenza].

Autor: Bykova NO, Gorbunov NV, Bolgarev AA, Savina MV, Ivanova TI, Egoiants MA, Vanin VF, Prozorovskaia MP
Jazyk: ruština
Zdroj: Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1991 Dec; Vol. 112 (12), pp. 617-9.
Abstrakt: The effect of free radical processes on the oxidation-phosphorylation activity in the liver of CBA-mice has been studied, using a model of toxic form viral infection. The EPR-spectroscopic and electrochemical methods applied in the study of animals infected with pathogenic form of the influenza virus made it possible to reveal a decrease in the activity of the respiratory chain in mitochondria. This seems likely to be due to accumulation of endogenic nitric oxide in the liver tissue.
Databáze: MEDLINE