| Autor: |
Lobão FA; Laboratório de Fisiologia e Bioquímica de Microrganismos, Universidade Estadual do Norte Fluminense, Campos dos Goytacazes, Brazil., Façanha AR, Okorokov LA, Dutra KR, Okorokova-Façanha AL |
| Jazyk: |
angličtina |
| Zdroj: |
FEMS microbiology letters [FEMS Microbiol Lett] 2007 Sep; Vol. 274 (1), pp. 17-23. |
| DOI: |
10.1111/j.1574-6968.2007.00811.x |
| Abstrakt: |
The effect of aluminum on dimorphic fungi Yarrowia lipolytica was investigated. High aluminum (0.5-1.0 mM AlK(SO(4))(2)) inhibits yeast-hypha transition. Both vanadate-sensitive H(+) transport and ATPase activities were increased in total membranes isolated from aluminum-treated cells, indicating that a plasma membrane H(+) pump was stimulated by aluminum. Furthermore, Al-treated cells showed a stronger H(+) efflux in solid medium. The present results suggest that alterations in the plasma membrane H(+) transport might underline a pH signaling required for yeast/hyphal development. The data point to the cell surface pH as a determinant of morphogenesis of Y. lipolytica and the plasma membrane H(+)-ATPase as a key factor of this process. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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