| Autor: |
Kovalenko TM, Osadchenko IO, Tsupykov OM, Pivneva TA, Shalamaĭ AS, Moĭbenko OO, Skybo HH |
| Jazyk: |
ukrajinština |
| Zdroj: |
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) [Fiziol Zh (1994)] 2006; Vol. 52 (5), pp. 21-7. |
| Abstrakt: |
The neuroprotective action by water-soluble form of quercetin was examined in gerbils after transient forebrain ischemia. The animals were exposed to 7 min of bilateral common carotid artery occlusion. Hippocampal CA 1 area was examined 7 days after ischemia-reperfusion. The average density of CA1 pyramidal neurons and GFAP-positive glial cells were counted in sham operated group, in ischemic group and in the groups treated with water-soluble form of quercetin. It was shown that quercetin revealed protective effect by decreasing of delayed neuronal death and reducing reactive astrogliosis after ischemia-reperfusion. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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