Scoring guide when deciding to accept an organ for a liver transplant.

Autor: Pareja-Ciuró F; Hepato-Pancreato-Biliary Surgery and Liver Transplant Unit, Virgen Del Rocío University Hospitals, Seville, Spain. Felipe.Pareja@terra.es, Alamo-Martinez JM, Barrera-Pulido L, Serrano-Díez J, Gomez-Bravo MA, García-Gonzalez I, Sousa-Martín JM, Pascasio-Acevedo JM, Porras-López FM, Gavilan-Carrasco F, Bernardos-Rodriguez A
Jazyk: angličtina
Zdroj: Transplantation proceedings [Transplant Proc] 2006 Oct; Vol. 38 (8), pp. 2382-4.
DOI: 10.1016/j.transproceed.2006.08.019
Abstrakt: Unlabelled: Our objective was establish a scoring system that allows a donor to be evaluated quickly and easily using a set of variables that are evaluated prior to the donation and another set that are evaluated during surgery.
Materials and Methods: Prior to the donation we analyzed age, medication requirements, natremia, hepatic biochemistry, gas levels, days in ICU, history of hypertension, and weight. A value of 40% was allocated to this group of factors. During the transplant we assessed the characteristics of the organ-shine, consistency, surface, edge, color, presence of steatosis, and atheromatosis. A value of 60% was allocated to this set. We established a scale of 1 to 10, only accepting organs scoring 5 or more points. Those grafts that received a score between 5 and 7.5 points were called suboptimal and those with over 7.5 points, optimal. We prospectively analyzed 133 donors whose organs were implanted.
Results: The survival rate at 1 year was 85%, and the rejection rate was 12%. The incidence of primary graft dysfunction was 8.2% (n = 11) and that of primary graft nonfunction 2.2% (n = 3). The incidence of primary graft dysfunction was greater within the group with fewer points (suboptimal). There were no differences between the optimal and suboptimal groups in terms of primary malfunction, survival, or rejection rate.
Conclusions: The score provided a guide to decide whether to accept viable organs for implantation, given that the point system was obtained quickly and easily. When greater than 5, it correlated with low rates of primary nonfunction (<3%) and of primary graft dysfunction (<15%), with acceptable survival at 1 year (>80%) and acute rejections rate (<15%).
Databáze: MEDLINE
Externí odkaz: