[Development of audiogenic kindling during the gestation period].

Autor: Samseishvili NT, Bilanishvili IG, Chachua TR, Tkeshelashvili BD, nanobashvili ZI
Jazyk: ruština
Zdroj: Georgian medical news [Georgian Med News] 2006 Sep (138), pp. 96-8.
Abstrakt: Some peculiarities of audiogenic kindling were studied in rats with genetically determined epileptic seizures during gestation period. In the period of gestation the development of audiogenic kindling in response to repetitive acoustic stimulation is markedly reduced. This indicates the strengthening of inhibitory processes in the brain. It is supposed that in the period of gestation in rats with genetically determined audiogenic seizures excess of sexual hormones and enhancement of GABA-ergic transmission causes marked reduction of development of audiogenic kindling.
Databáze: MEDLINE