| Autor: |
Castrogiovanni P; Department of Neuroscience, University of Siena, Siena, Italy., Pieraccini F, Iapichino S, Pacchierotti C, Bossini L, Truglia E, Malpassi C, Natale B |
| Jazyk: |
angličtina |
| Zdroj: |
CNS spectrums [CNS Spectr] 2001 Mar; Vol. 6 (3), pp. 210-3. |
| DOI: |
10.1017/s1092852900008580 |
| Abstrakt: |
Abnormal light-related behaviors have been described for patients with panic disorder (PD). The present study was undertaken to investigate the retinal light response in PD using electroretinography (ERG). The authors conducted b-wave ERG measurements with a bright light (after dark adaptation) in 28 patients with PD and 28 control subjects. There were no significant differences in the mean b-wave amplitude between the two groups, but the retinal response to light in PD patients was generally lower than in healthy subjects. A large interindividual variability was found; also noted was a significant difference in the mean b-wave amplitude between the right and left eyes in the control group. The data indicate subtle variation of retinal photosensitivity in a subgroup of patients with PD. Because dopaminergic retinal activity affects b-ERG amplitude, the authors hypothesize that the dopaminergic system is involved in the response to light in PD patients. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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