Multifocal choroiditis in disseminated Cryptococcus neoformans infection.

Autor: Andreola C; Department of Ophthalmology, AIDS Section, Centro Previdenciário de Niterói, Rio de Janeiro, Brazil., Ribeiro MP, de Carli CR, Gouvea AL, Curi AL
Jazyk: angličtina
Zdroj: American journal of ophthalmology [Am J Ophthalmol] 2006 Aug; Vol. 142 (2), pp. 346-8.
DOI: 10.1016/j.ajo.2006.03.024
Abstrakt: Purpose: To report an uncommon case of multifocal choroiditis as the result of disseminated Cryptococcus neoformans infection in a patient who is HIV-positive.
Design: Interventional case report.
Methods: A 27-year-old HIV-positive woman with fever, headache, and vomiting was examined. Lumbar puncture was performed and revealed C neoformans infection. Her condition evolved with sudden bilateral blindness and deafness. Ophthalmologic examination revealed multiple yellowish choroidal lesions in the posterior pole of both eyes.
Results: Postmortem examination showed disseminated C neoformans infection. Histologic examination of the eyes confirmed the presence of C neoformans in the choroiditis.
Conclusion: Multifocal choroiditis in C neoformans infection is a rare ophthalmic manifestation. The recognition of this condition by ophthalmologists can help physicians to diagnose a disseminated and fatal disease.
Databáze: MEDLINE
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