| Autor: |
Wilkinson TG 2nd; Department of Biology, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182-4614, USA., Kedar GC, Lee C, Guzmán EC, Smith DW, Zyskind JW |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of bacteriology [J Bacteriol] 2006 Jun; Vol. 188 (12), pp. 4573-6. |
| DOI: |
10.1128/JB.00089-06 |
| Abstrakt: |
To examine whether methylation of the GATC sites present in the dnaA promoter region is responsible for the strict temporal coordination of initiation events at oriC as measured by the synchrony of initiation, we introduced point mutations eliminating three (TGW1) and five (TGW2) of the six GATC sites present in the dnaA promoter region. All of the strains containing these mutations, including the one with five GATC sites eliminated, initiated chromosomal replication synchronously. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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