| Autor: |
Cui X; Department of Chemistry, University of Science and Technology of China, Hefei 230026, China., Li Z, Tao CZ, Xu Y, Li J, Liu L, Guo QX |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2006 Jun 08; Vol. 8 (12), pp. 2467-70. |
| DOI: |
10.1021/ol060585n |
| Abstrakt: |
N,N-Dimethyl-beta-alanine was found to be a more powerful phosphine-free ligand than the previously reported ligand, N,N-dimethylglycine, in the Pd-catalyzed Heck reaction for a variety of aryl bromides, aryl iodides, and activated aryl chlorides with a practical turnover number of 10(3). Both kinetic and theoretical studies suggested that N,N-dimethyl-beta-alanine led to faster oxidative addition of an aryl halide to Pd than N,N-dimethylglycine. [reaction: see text] |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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