| Autor: |
Boldasov VK, Kalinina NA, Revunova OV, Guseva VM, Leonov VM, Sukhinin VP, Il'enko VI |
| Jazyk: |
ruština |
| Zdroj: |
Voprosy virusologii [Vopr Virusol] 1991 Sep-Oct; Vol. 36 (5), pp. 389-92. |
| Abstrakt: |
Deitiforin in HEp-2 cell culture was shown to inhibit replication of the reference PIV-3 strain when administered 1 hour before virus inoculation. The most marked effect of the drug was observed in the first 4 days of observation. In experimental newborn mice infected with parainfluenza virus 3 deitiforin protected the animals from developing the infection. In humans given deitiforin reaction to vaccination was found to develop 5-6 times more rarely than in the control group, PIV-3 could be isolated twice as rarely, and a diagnostically significant rise of specific antibody levels was observed less frequently. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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