Autor: |
Klos KJ; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Ahlskog JE, Josephs KA, Apaydin H, Parisi JE, Boeve BF, DeLucia MW, Dickson DW |
Jazyk: |
angličtina |
Zdroj: |
Neurology [Neurology] 2006 Apr 11; Vol. 66 (7), pp. 1100-2. |
DOI: |
10.1212/01.wnl.0000204179.88955.fa |
Abstrakt: |
The authors assessed the frequency of spinal cord alpha-synuclein pathology in neurologically asymptomatic individuals older than 60 years of age (N = 106). Using alpha-synuclein immunohistochemistry, nine cases (8%) had incidental Lewy neurites in the intermediolateral column and at least some alpha-synuclein pathology in the dorsal motor nucleus of the vagus, locus ceruleus, and central raphe nucleus. Sparse alpha-synuclein pathology was also detected in the substantia nigra, basal forebrain, amygdala, or cortex in all but two cases. |
Databáze: |
MEDLINE |
Externí odkaz: |
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