| Autor: |
Kuziv OIe, Bodnar IaIa, Kuziv PP, Klymchuk LF, Zavads'ka TS, Derpak IuIu |
| Jazyk: |
ukrajinština |
| Zdroj: |
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) [Fiziol Zh (1994)] 2005; Vol. 51 (5), pp. 71-8. |
| Abstrakt: |
Processes of free radical lipid oxidation (FLI), endogenic intoxication, antioxidant protection system (AOP) and morphology of a liver at tetrachlormethane hepatosis and its correction by a complete fasting have been assessed. Two chains of pathogenesis of tetrachlormethane hepatosis have been determined: the metabolic chain that is accompanied by sharp activation of free radical lipid oxidation under emaciation of antioxidant protection system and increasing endotoxemia; and the ischemic chain that enhances the processes of dystrophy and necrosis of hepatocytes and neofibrous formations. The correction by a complete fasting promoted normalization of free radical lipid oxidation at simultaneous rising of antioxidant protection system function, decreasing of a level of endogenic intoxication and conservation of hepatocytes' structure, improving recovering possibilities and prevents dystrophic and necrotic changes and neofibrous formations in the liver at tetrachlormethane hepatosis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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