Severe hemolytic anemia due to auto anti-N.

Autor: Immel CC; Transfusion Medicine Service, UNC Hospitals, 1021 East Wing, 101 Manning Drive, Chapel Hill, NC 27514, USA., McPherson M, Hay SN, Braddy LR, Brecher ME
Jazyk: angličtina
Zdroj: Immunohematology [Immunohematology] 2005; Vol. 21 (2), pp. 63-5.
Abstrakt: Auto anti-N is infrequently encountered and, in most reported cases, does not cause clinical hemolysis. This case reports an auto anti-N associated with severe hemolytic anemia (Hb=2.7 g/dL) in a 6-year-old Caucasian girl with a history of vomiting, fever, and abdominal pain. Upon admission, she was found to have a metabolic acidosis, secondary to her severe anemia, with abnormal liver function tests. As in three other case reports, the autoimmune hemolytic anemia resolved, with disappearance of the auto anti-N, after corticosteroid therapy.
Databáze: MEDLINE