Investigating the relationship between hemodynamic and metabolic parameters in portal triade occlusion following hemorrhagic shock.

Autor:	Fontelles MJ; Trauma Surgery Division, Department of Surgery, Faculty of Medical Sciences, Unicamp, Campinas, Brazil. mikefox@uol.com.br, Mantovani M, Hirano ES, Morandin RC
Jazyk:	angličtina
Zdroj:	Acta cirurgica brasileira [Acta Cir Bras] 2005 Jan-Feb; Vol. 20 (1), pp. 22-7.
DOI:	10.1590/s0102-86502005000100005
Abstrakt:	Purpose: To determine whether metabolic and hemodynamic parameters are "mathematically" coupled in rats submitted to portal triad occlusion following controlled hemorrhagic shock state. Methods: Pearson's coefficient (r-value) analysis was performed. Differences considered significant at p < 0.05 and -0.50 > r > 0.50. Results: It was observed that there is a direct proportional relationship to HCO3- with pCO2 (r = 0.66), base deficit (r = 0.87) and inverse with serum lactate (r = -0.54). pCO2 was directly associated with MAP (r = 0.51), and inversely with pH (r = -0.64). Hematocrit was directly associated with HR (r = 0.72) and CI (r = 0.76), and serum lactated was inversely associated with base deficit (r = -0.61). Conclusion: In rats submitted to Pringle's maneuver during 15 minutes following hemorrhagic shock state, there is a mathematical coupling with a very good correlation between several hemodynamic and metabolic variables.
Databáze:	MEDLINE
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