| Autor: |
Hulin B; Pfizer Global Research and Development, Eastern Point Road, Groton, Connecticut 06340, USA. bernard_hulin@groton.pfizer.com, Newton LS, Cabral S, Walker AJ, Bordner J |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2004 Nov 11; Vol. 6 (23), pp. 4343-5. |
| DOI: |
10.1021/ol048140r |
| Abstrakt: |
1,5-Cyclooctadiene can be stereoselectively transformed into a substituted bicyclo[3.3.0]octane ring system under palladium catalysis with concomitant formation of three carbon-carbon bonds. Reaction with an aryl iodide or triflate and malonate gives an exo-endo product, while the reaction with a malonate in the presence of oxygen affords a bis-endo adduct. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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