Cold sensitivity of thermophilic and mesophilic RNA polymerases.

Autor: Kulbachinskiy A; Institute of Molecular Genetics, Moscow, Russia. akulb@img.ras.ru, Bass I, Bogdanova E, Goldfarb A, Nikiforov V
Jazyk: angličtina
Zdroj: Journal of bacteriology [J Bacteriol] 2004 Nov; Vol. 186 (22), pp. 7818-20.
DOI: 10.1128/JB.186.22.7818-7820.2004
Abstrakt: RNA polymerase from mesophilic Deinococcus radiodurans displays the same cold sensitivity of promoter opening as RNA polymerase from the closely related thermophilic Thermus aquaticus. This suggests that, contrary to the accepted view, cold sensitivity of promoter opening by thermophilic RNA polymerases may not be a consequence of their thermostability.
Databáze: MEDLINE