Tissue reaction against a self-setting calcium phosphate cement set in bone or outside the organism.

Autor: Frayssinet P; Depuy-Bioland, 132 Rte d'Espagne, 31100 Toulouse, France. patrickf@worldnet.fr, Roudier M, Lerch A, Ceolin JL, Deprès E, Rouquet N
Jazyk: angličtina
Zdroj: Journal of materials science. Materials in medicine [J Mater Sci Mater Med] 2000 Dec; Vol. 11 (12), pp. 811-5.
DOI: 10.1023/a:1008909714090
Abstrakt: Calcium phosphate cements are able to set in situ when injected into bone tissue. We evaluated the tissue reaction occurring when a DCPD-based calcium phosphate cement was either set within the bone or implanted when already set. The samples were implanted in rabbit condyles and examined histologically after 8 and 16 weeks. The relative bone surface, the fibrous capsule around the implants and the implant section surface were measured. Solid material seemed to be better tolerated than paste implants. More bone was found at the solid implant contact whatever the implantation time and the solid material degraded much less rapidly. In conclusion, the physico-chemical modification of the biological environment occurring during setting increases the foreign body reaction against the material.
(Copyright 2000 Kluwer Academic Publishers)
Databáze: MEDLINE
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