| Autor: |
Frohman EM; Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA. elliot.frohman@utsouthwestern.edu, Dewey RB, Frohman TC |
| Jazyk: |
angličtina |
| Zdroj: |
Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2004 Jun; Vol. 10 (3), pp. 322-5. |
| DOI: |
10.1191/1352458504ms1043oa |
| Abstrakt: |
Patients with MS exhibit a broad diversity of ocular motor syndromes. We describe a patient with relapsing-remitting MS who developed an unusual variation of the dorsal midbrain syndrome, characterized by monocular convergent-retraction nystagmus in the right eye, accompanied by divergent-retraction nystagmus in the fellow eye upon attempted upward gaze. Examination also revealed a skew deviation with a left hyperdeviation and severe adduction limitation in the left eye during attempted right gaze. We propose that a left INO accounted for the inability of the left eye to adduct (and result in convergent-retraction) during attempted upward saccades. We consider the pathophysiologic mechanisms responsible for our observations and review important details of the dorsal midbrain ocular motor circuitry. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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