Autor: |
Bartram PA; Department of Reproduction, School of Veterinary Medicine, University of California, Davis 95616., Glenn JS, Lasslo LL |
Jazyk: |
angličtina |
Zdroj: |
Journal of the American Veterinary Medical Association [J Am Vet Med Assoc] 1992 Aug 01; Vol. 201 (3), pp. 445-8. |
Abstrakt: |
Ovine contagious foot rot may cause lameness in sheep, resulting in decreased wool growth and low weight gain. Affected neonatal lambs are difficult to treat, and treatment is labor intensive; thus, a method of prevention is warranted. Vaccination of ewes with a multivalent vaccine in an oil adjuvant induced development of antibody to the somatic O antigen of Bacteroides nodosus, and this antibody was detected in serum of newborn lambs after consumption of colostrum from the vaccinated ewes. Antibody titers were determined in 48 unvaccinated ewe/lamb pairs, and in 50 once-vaccinated and 78 twice-vaccinated pairs. Serum and colostrum O-agglutinin titers to B nodosus were determined by a microtitration agglutination test. Lambs from vaccinated ewes had significantly (P less than 0.05) higher O-agglutinin titers than those from unvaccinated ewes, and double vaccination of ewes resulted in the highest potentially protective titers (greater than 1:2,400) in ewes and lambs. |
Databáze: |
MEDLINE |
Externí odkaz: |
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