Autor: |
Kondratenko RM; Bashkortostan State Medical University, Ufa, Bashkortostan, 450074 Russia., Baltina LA, Vasil'eva EV, Baltina LA, Ismagilova AF, Nasyrov KhM, Baschenko NZh, Kireeva RM, Fridman SM, Tolstikov GA |
Jazyk: |
ruština |
Zdroj: |
Bioorganicheskaia khimiia [Bioorg Khim] 2004 Jan-Feb; Vol. 30 (1), pp. 61-7. |
DOI: |
10.1023/b:rubi.0000015774.09619.80 |
Abstrakt: |
New cysteine-containing derivatives of glycyrrhizic acid were synthesized by its coupling with Cys(Bzl) esters or the Cys(Bzl)-Val-OBu(t) dipeptide by the active ester method (DCC/HOSu) or by Woodward's reagent K. The derivatives with Cys(Bzl) and Cys(Bzl)-Val residues attached to the carbohydrate part of the molecule stimulated the primary immune response and the reaction of delayed-type hypersensitivity in mice at a dose of 2 mg/kg. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2004, vol. 30, no. 1; see also http://www.maik.ru. |
Databáze: |
MEDLINE |
Externí odkaz: |
|