| Autor: |
Zhukovskiĭ IuG; Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences, St. Petersburg, Russian Federation. zhuk@zhuk.mail.iephb.ru, Kuznetsova LP, Sochilina EE, Veksler KV |
| Jazyk: |
ruština |
| Zdroj: |
Ukrains'kyi biokhimichnyi zhurnal (1999 ) [Ukr Biokhim Zh (1999)] 2003 May-Jun; Vol. 75 (3), pp. 67-70. |
| Abstrakt: |
1- and 2-thionaphthylacetates were tested as cholinesterase substrates. It was shown that the butyrilcholinesterase from horse serum can hydrolize these compounds. The hydrolysis velocity of 1-thionaphthylacetate was comparable with hydrolysis velocity of acetylthiocholine (the well known cholinesterase substrate), but 2-thionaphthylacetate was hydrolysed more slowly. The values of the kinetic parameters V and K(m) for butyrylcholinesterase hydrolysis of 1- and 2-thionaphthylacetates were determined. It was offered to use 1-thionaphthylacetates as the substrate for cholinesterases. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
