| Autor: |
Meirelles LR; Department of Anatomic Pathology, School of Medicine, State University of Campinas (UNICAMP), Campinas, Brazil., Billis A, Cotta AC, Nakamura RT, Caserta NM, Prando A |
| Jazyk: |
angličtina |
| Zdroj: |
International urology and nephrology [Int Urol Nephrol] 2002; Vol. 34 (3), pp. 345-50. |
| DOI: |
10.1023/a:1024405920019 |
| Abstrakt: |
Prostatic atrophy may be histologically and at ultrasound similar to adenocarcinoma causing diagnostic confusion, its frequency increases with age but the etiopathogenesis is unknown. Based on a systematic study in autopsies previously done by one of us, ischemia due to local intense arteriosclerosis seems to be a potential factor for its pathogenesis. Absent blood flow in areas of prostatic atrophy might be a further evidence for a possible role of ischemia. From a total of 298 patients biopsied and studied by gray-scale and color Doppler transrectal ultrasound in the period 1998 to 2001, 33 patients had suspicious lesions (37 hypoechoic nodules and 3 heterogeneous lesions) showing prostatic atrophy as the only diagnosis on all these biopsied lesions. Adenocarcinoma, high-grade intraepithelial neoplasia or other atypical lesions were absent in all patients. On color Doppler the suspicious areas showed absent flow in 24/40 (60%), present flow in 12/40 (30%), and increased flow in 4/40 (10%) of the lesions. Absent flow in the majority of the lesions studied may be a further evidence for a possible role of local ischemia in the etiopathogenesis of prostatic atrophy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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