| Autor: |
Pietrantoni A; Department of Ultrastructure, Istituto Superiore di Sanità, Rome, Italy., Di Biase AM, Tinari A, Marchetti M, Valenti P, Seganti L, Superti F |
| Jazyk: |
angličtina |
| Zdroj: |
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2003 Aug; Vol. 47 (8), pp. 2688-91. |
| DOI: |
10.1128/AAC.47.8.2688-2691.2003 |
| Abstrakt: |
We recently demonstrated that lactoferrin, an antimicrobial glycoprotein, can inhibit adenovirus infection by competing for common glycosaminoglycan receptors. This study further characterizes the antiadenovirus activity of the protein, thus demonstrating that lactoferrin neutralizes infection by binding to adenovirus particles and that its targets are viral III and IIIa structural polypeptides. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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